Jurgen Klopp could be without up to nine first-team players when Liverpool host Leicester in the Premier League on Saturday.
The Reds have been dealt an injury crisis early into their title defence, with star defenders Virgil van Dijk and Joe Gomez set to miss the majority of the season with knee injuries.
Trent Alexander-Arnold is currently nursing a calf problem, Andy Robertson and Jordan Henderson have sustained leg injuries on international duty and Fabinho is still recovering from a thigh issue.
Thiago Alcantara is also out with a knee injury, while Mohamed Salah is unlikely to line up against the Foxes after testing positive for Covid-19.
And long-term absentee Alex Oxlade-Chamberlain is still not ready to return.
Klopp will therefore have to put together a makeshift XI when former manager Brendan Rodgers’ side visit Anfield after the international break.
If he decides to deploy a 4-3-3 formation on Merseyside, Alisson is fit and could start in goal behind a back four consisting of James Milner, Joel Matip, Nat Phillips and Kostas Tsimikas.
Milner has proven capable of operating at right-back in recent years and could provide some much-needed experience in Van Dijk’s absence, while academy graduate Phillips impressed in the recent win over West Ham and could earn another start, with Joel Matip and Kostas Tsimikas making up the rest of the back four.
Youngster Curtis Jones could then start alongside Georginio Wijnaldum and Naby Keita in a three-man midfield, with Diogo Jota, Roberto Firmino and Sadio Mane deployed upfront.
However, Neco Williams is another solid option for Klopp at right-back, and bringing the 19-year-old in could see Milner move into midfield alongside Wijnaldum and Keita.
Rhys Williams, 19, has also impressed at centre-half of late and will battle it out with Phillips for a starting spot alongside Matip at the heart of the defence.
Klopp may decide to field a 4-2-3-1 and bring Takumi Minamino into the fold on the right flank, which could see Wijnaldum and Milner form a two-man central midfield and in-form star Jota operate as a false nine.
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Liverpool’s three best potential starting line-ups vs Leicester
(4-3-3) – Alisson; Milner, Matip, Phillips, Tsimikas; Jones, Wijnaldum, Keita; Jota, Firmino, Mane
(4-3-3) – Alisson; N.Williams, Matip, Phillips, Tsimikas; Wijnaldum, Milner, Keita; Jota, Firmino, Mane
(4-2-3-1) – Alisson; N.Williams, Matip, R.Williams, Tsimikas; Wijnaldum, Milner; Minamino, Firmino, Mane; Jota
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